circRNA basic information
circBase ID: hsa_circ_0014130
Name: hsa_circ_PIP5K1A
Synonym: -
Host Gene: hsa-miR-136-5p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human NSCLC cell lines (PC-9, A549)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: Bcl-2
Associated microRNA: hsa-miR-136-5p
Biological function: promoted the proliferation and invasion and Inhibits Apoptosis
Molecular mechanism: upregulating Bcl-2 partially via sponging hsa-miR-136-5p
Survival: -
Supported No.:
 4
Description:

hsa_circ_0014130 functions as a tumor promoter in NSCLC to promote tumor growth through upregulating Bcl-2 partially via sponging miR-136-5p.

Other information
Title:

Circular RNA hsa_circ_0014130 Inhibits Apoptosis in Non-Small Cell Lung Cancer by Sponging miR-136-5p and Upregulating BCL2.

Journal: Mol Cancer Res
Published: 2020/2/16
PubMed ID: 32060230