circRNA basic information
circBase ID: -
Name: hsa_circ_MDM2
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: colorectal cancer cell lines (HCT116, SW48, RKO), osteosarcoma cell lines (U2OS, SJSA), normal human fibroblasts cells (BJ)
circRNA-disease information
Detected method:
S
Detected method confidence Low
Expression pattern:
UP
Associated gene: p53
Associated microRNA: -
Biological function: Controls Cell Cycle Progression
Molecular mechanism: by Suppressing p53 Levels
Survival: -
Supported No.:
 1
Description:

Our results on the initial characterization of circ-MDM2 identify a new player from the MDM2 locus that suppresses p53 levels and cell cycle progression.
Other information
Title:

A Circular RNA from the MDM2 Locus Controls Cell Cycle Progression by Suppressing p53 Levels.

Journal: Mol Cell Biol
Published: 2020/2/12
PubMed ID: 32041821