circRNA basic information
circBase ID: -
Name: hsa_circ_ZKSCAN1
Synonym: circ-ZKSCAN1
Host Gene: hsa-miR-330-5p
 
 
 
Disease basic information
DO ID:
3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: NSCLC cell lines (A549, H1299, H460, H1650, NCI-2228), human bronchial epithelial cells (HBE)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FAM83A
Associated microRNA: hsa-miR-330-5p
Biological function: promote cells migration and invasion
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
1
Description:

Circ-ZKSCAN1 is a key positive regulator of NSCLC, and clarifies the potential molecular mechanism of the new circ-ZKSCAN1/miR-330-5p/FAM83A feedback loop in promoting the progress of NSCLC.

Other information
Title:

Circ-ZKSCAN1 regulates FAM83A expression and inactivates MAPK signaling by targeting miR-330-5p to promote non-small cell lung cancer progression.

Journal: Transl Lung Cancer Res
Published: 2020/2/6
PubMed ID: 32010565