circRNA basic information
circBase ID: hsa_circ_0007255
Name: hsa_circ_KIF4A
Synonym: -
Host Gene: hsa-miR-335-5p
 
 
 
Disease basic information
DO ID:
1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: BC cell lines (T47D, MCF_7, MB231, MB468), normal human breast epithelial cells (MCF_10A)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SIX2
Associated microRNA: hsa-miR-335-5p
Biological function: -
Molecular mechanism: via hsa-miR-335-5p/SIX2 axis
Survival: -
Supported No.:
4
Description:

Circ_0007255 functioned as a novel oncogene in the progression of BC by regulating miR-335-5p/SIX2 axis, and might be a promising biomarker for BC treatment.

Other information
Title:

Circular RNA 0007255 regulates the progression of breast cancer through miR-335-5p/SIX2 axis.

Journal: Thorac Cancer
Published: 2020/1/22
PubMed ID: 31962380