circRNA basic information
circBase ID: hsa_circ_0062389
Name: hsa_circ_PI4KA
Synonym: -
Host Gene: hsa-miR-103a-3p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human lung cancer cell lines (H1650, H23, H522, A549, H1703, H460), human bronchiolar epithelial cell line (BEAS-2B)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CCNE1
Associated microRNA: hsa-miR-103a-3p
Biological function: -
Molecular mechanism: sponging hsa-miR-103a-3p to mediate CCNE1 expression
Survival: poor
Supported No.:
 1
Description:

Our results showed that the hsa_circ_0062389/miR-103a-3p/CCNE1 axis might contribute to the tumorigenesis of NSCLC, which provided a new strategy for cancer treatment.
Other information
Title:

hsa_circ_0062389 promotes the progression of non-small cell lung cancer by sponging miR-103a-3p to mediate CCNE1 expression.

Journal: Cancer Genet
Published: 2020/1/22
PubMed ID: 31962276