circRNA basic information
circBase ID: hsa_circ_0061825
Name: hsa_circ_TFF1
Synonym: -
Host Gene: hsa-miR-326
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: breast cancer cell lines (MCF_7, MDA_MB_453, BT_549, MDA_MB_231), normal breast cells (MCF_10A)
circRNA-disease information
Detected method:
Q
S
M
Detected method confidence High
Expression pattern:
UP
Associated gene: TFF1
Associated microRNA: hsa-miR-326
Biological function: promote cell proliferation, migration, invasion and EMT
Molecular mechanism: acted as a ceRNA of TFF1 by sponging hsa-miR-326
Survival: -
Supported No.:
 3
Description:

Circ-TFF1 is a facilitator in breast cancer relying on TFF1 by absorbing miR-326, providing a novel promising target for BC treatment.
Other information
Title:

Circular RNA hsa_circ_0061825 (circ-TFF1) contributes to breast cancer progression through targeting miR-326/TFF1 signalling.

Journal: Cell Prolif
Published: 2020/1/22
PubMed ID: 31961997