circRNA basic information
circBase ID: -
Name: rno_circ_ZNF609
Synonym: -
Host Gene: rno-miR-184
 
 
 
Disease basic information
DO ID:
 11382
DO name: corneal neovascularization
Disease details: corneal neovascularization
Species: rat
Species details: rat
Sample type: tissue, cell line
Sample type details: human corneal epithelial keratinocytes (HCEKs)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: Akt and VEGF signaling pathway
Associated microRNA: rno-miR-184
Biological function: promote cell proliferation, migration in vitro, and angiogenesis in vivo
Molecular mechanism: acting as a sponge of miR-184
Survival: -
Supported No.:
 1
Description:

cZNF609/miR-184 interaction regulated the downstream Akt and VEGF signaling pathway. Intervention of cZNF609 and miR-184 may serve as a potential strategy for pathological corneal neovascularization treatment.
Other information
Title:

Circular RNA-ZNF609 regulates corneal neovascularization by acting as a sponge of miR-184.

Journal: Exp Eye Res
Published: 2020/1/20
PubMed ID: 31954666