circRNA basic information
circBase ID: -
Name: gga_circ_HMGCL
Synonym: chr23:5549365-5549645
Host Gene: gga-miR-6702-5p, gga-miR-1662, gga-miR-34b-5p, gga-miR-6611-5p, gga-miR-6641-5p
 
 
 
Disease basic information
DO ID:
 934
DO name: viral infectious disease
Disease details: avian leukosis virus subgroup
Species: chicken
Species details: chicken
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: gga-miR-6702-5p, gga-miR-1662, gga-miR-34b-5p, gga-miR-6611-5p, gga-miR-6641-5p
Biological function: -
Molecular mechanism: miRNA sponge, involved in immune pathways
Survival: -
Supported No.:
 1
Description:

Two randomly selected circRNAs that were upregulated in ALV-J-resistant chickens (chr1:194735582-194744050- and chr23:5549365-5549645-) and two randomly circRNAs that were downregulated in ALVJ-resistant chickens (chr8:1033880-1047222- and chr5:58225735-58230830-) were selected to validate the expression levels of the significantly differentially expressed circRNAs by quantitative real-time polymerase chain reaction (qRT-PCR). The qRT-PCR data for the four circRNAs was consistent with the trends observed using circRNA sequencing.
Other information
Title:

Circular RNA alterations are involved in resistance to avian leukosis virus subgroup-J-induced tumor formation in chickens.

Journal: Oncotarget
Published: 2017/4/19
PubMed ID: 28415618