circRNA basic information
circBase ID:
hsa_circ_0039411
Name:
hsa_circ_MMP2
Synonym:
-
Host Gene:
hsa-miR-136-5p
Disease basic information
DO ID:
684
DO name:
hepatocellular carcinoma
Disease details:
hepatocellular carcinoma
Species:
human
Species details:
human
Sample type:
tissue, cell line, PDX
Sample type details:
human liver cancer cell lines (97H, LM3, SMMC_7721, HepG2), human normal liver cell line (L02)
circRNA-disease information
Detected method:
Q
Detected method confidence
High
Expression pattern:
UP
Associated gene:
matrix metallopeptidase 2 (MMP2)
Associated microRNA:
hsa-miR-136-5p
Biological function:
-
Molecular mechanism:
led to the upregulation of its host gene matrix metallopeptidase 2 (MMP2) via the sponging of hsa-miR-136-5p
Survival:
-
Supported No.:
1
Description:
Exosome-transmitted circ_MMP2 promotes hepatocellular carcinoma metastasis by upregulating MMP2.
Other information
Title:
Exosome-transmitted circ_MMP2 promotes hepatocellular carcinoma metastasis by upregulating MMP2.
Journal:
Mol Oncol
Published:
2020/1/17
PubMed ID:
31944556