circRNA basic information
circBase ID: -
Name: -
Synonym: circRNA_010567
Host Gene: mmu-miR-141
 
 
 
Disease basic information
DO ID:
 114
DO name: heart disease
Disease details: diabetic myocardial fibrosis
Species: mouse
Species details: mouse
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: TGF-beta1
Associated microRNA: mmu-miR-141
Biological function: promotes myocardial fibrosis
Molecular mechanism: suppressing mmu-miR-141 by targeting TGF-beta1
Survival: -
Supported No.:
 1
Description:

CircRNA_010567/miR-141/TGF-beta1 axis plays an important regulatory role in the diabetic mice myocardial fibrosis model.
Other information
Title:

A novel identified circular RNA, circRNA_010567, promotes myocardial fibrosis via suppressing miR-141 by targeting TGF-beta1.

Journal: Biochem Biophys Res Commun
Published: 2017/4/17
PubMed ID: 28412345