circRNA basic information
circBase ID: -
Name: hsa_circ_LARP4
Synonym: -
Host Gene: hsa-miR-1323
 
 
 
Disease basic information
DO ID:
3748
DO name: esophagus squamous cell carcinoma
Disease details: esophageal squamous cell carcinoma
Species: human
Species details: human
Sample type: cell line
Sample type details: normal human esophageal epithelial cell line (HEEPIC), ESCC cell lines (ECA109, TE-1, KYSE30, KYSE410)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: PTEN/PI3K/AKT pathway
Associated microRNA: hsa-miR-1323
Biological function: inhibitive cell proliferation, migration, and promotive apoptosis
Molecular mechanism: sponges hsa-miR-1323 and modulating PTEN/PI3K/AKT pathway
Survival: -
Supported No.:
1
Description:

CircLARP4 sponges miR-1323 and hampers tumorigenesis of ESCC through modulating PTEN/PI3K/AKT pathway.

Other information
Title:

Circular RNA_LARP4 Sponges miR-1323 and Hampers Progression of Esophageal Squamous Cell Carcinoma Through Modulating PTEN/PI3K/AKT Pathway.

Journal: Dig Dis Sci
Published: 2020/1/4
PubMed ID: 31897898