circRNA basic information
circBase ID: -
Name: hsa_circ_CAMK2A
Synonym: circ-CAMK2A
Host Gene: hsa-miR-615-5p
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: LUAD cell lines (NCI-H1299, NCI-H1975, HCC827, NCI-H23, A549, SPC-A1), normal HBE cell line
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: fibronectin 1
Associated microRNA: hsa-miR-615-5p
Biological function: promote proliferation and invasion
Molecular mechanism: Circ-CAMK2A up-regulates the expression level of fibronectin 1 by sponging hsa-miR-615-5p, thereby increasing MMP2 and MMP9 expression to promote the metastasis of LUAD
Survival: -
Supported No.:
 1
Description:

Circ-CAMK2A plays a crucial role in the metastasis of LUAD, at least partially, by regulating the miR-615-5p/fibronectin 1 axis.
Other information
Title:

The novel circular RNA circ-CAMK2A enhances lung adenocarcinoma metastasis by regulating the miR-615-5p/fibronectin 1 pathway.

Journal: Cell Mol Biol Lett
Published: 2020/1/1
PubMed ID: 31889960