circRNA basic information
circBase ID: -
Name: hsa_circ_ABCB10
Synonym: -
Host Gene: hsa-miR-670-3p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human HCC cell lines (HepG2, PLC, SK-Hep1, HCCLM3, Huh7, Hep3B), human normal liver cell lines (LO2)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HMG20A
Associated microRNA: hsa-miR-670-3p
Biological function: promote proliferation and invasion
Molecular mechanism: miRNA sponge
Survival: poor
Supported No.:
 2
Description:

circABCB10 promoted HCC progression by modulating the miR-670-3p/HMG20A axis, and circABCB10 may be a potential therapeutic target for HCC.
Other information
Title:

Circular RNA ABCB10 promotes hepatocellular carcinoma progression by increasing HMG20A expression by sponging miR-670-3p.

Journal: Cancer Cell Int
Published: 2020/1/1
PubMed ID: 31889891