circRNA basic information
circBase ID: -
Name: hsa_circ_TTBK2
Synonym: -
Host Gene: hsa-miR-520b
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: glioma cell lines (A172, U251), normal human astrocytes (NHA)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: EZH2
Associated microRNA: hsa-miR-520b
Biological function: promote cell proliferation, apoptosis, and invasion
Molecular mechanism: increase EZH2
Survival: -
Supported No.:
 4
Description:

Circ-TTBK2/miR-520b/EZH2 axis modulated cell proliferation, apoptosis, and invasion in glioma cell lines, and might serve as potential targets for glioma diagnosis and therapy.
Other information
Title:

Circular RNA TTBK2 promotes the development of human glioma cells via miR-520b/EZH2 axis.

Journal: Eur Rev Med Pharmacol Sci
Published: 2019/12/21
PubMed ID: 31858557