circRNA basic information
circBase ID: -
Name: hsa_circ_PTPRA
Synonym: -
Host Gene: hsa-miR-636
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: BC cell lines (T24, UM-UC-3)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: KLF9
Associated microRNA: hsa-miR-636
Biological function: suppresses proliferation
Molecular mechanism: sponging hsa-miR-636 and upregulating KLF9
Survival: better
Supported No.:
 1
Description:

circPTPRA acts as a tumor suppressor in BC, and suggests that this circRNA may be a novel prognostic biomarker and therapeutic target in BC.
Other information
Title:

CircPTPRA acts as a tumor suppressor in bladder cancer by sponging miR-636 and upregulating KLF9.

Journal: Aging (Albany NY)
Published: 2019/12/11
PubMed ID: 31821171