circRNA basic information
circBase ID: hsa_circ_0006260
Name: hsa_circ_SLC41A2
Synonym: ciRs-6
Host Gene: hsa-miR-653
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human bladder cancer cell lines (T24, UM-UC-3)
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: Marchˇ¤1
Associated microRNA: hsa-miR-653
Biological function: suppresses proliferation
Molecular mechanism: upregulates March1
Survival: better
Supported No.:
 1
Description:

Our study identifies an oncogenic role of ciRs-6 and suggests its usefulness as a novel biomarker for bladder cancer diagnosis and prognosis and as a therapeutic target for bladder cancer.
Other information
Title:

ciRs-6 upregulates March1 to suppress bladder cancer growth by sponging miR-653.

Journal: Aging (Albany NY)
Published: 2019/12/11
PubMed ID: 31819015