circRNA basic information
circBase ID: -
Name: hsa_circ_ADAM9
Synonym: -
Host Gene: hsa-miR-217
 
 
 
Disease basic information
DO ID:
 1793
DO name: pancreatic cancer
Disease details: pancreatic cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: PANC1, MiaPaca2, SW1990, Capan1, BxPC3, normal pancre-atic ductal epithelial cell line (HPDE)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PRSS3
Associated microRNA: hsa-miR-217
Biological function: promote proliferation, migration and invasion
Molecular mechanism: sponging hsa-miR-217 and upregulating PRSS3 expression
Survival: poor
Supported No.:
 1
Description:

the ceRNA regulatory network of circ-ADAM9/miR-217/PRSS3 plays a pivotal role in PC progression by the regulation of ERK/VEGF signalling pathway.
Other information
Title:

Circular RNA ADAM9 facilitates the malignant behaviours of pancreatic cancer by sponging miR-217 and upregulating PRSS3 expression.

Journal: Artif Cells Nanomed Biotechnol
Published: 2019/12/8
PubMed ID: 31810373