circRNA basic information
circBase ID: hsa_circ_0003418
Name: -
Synonym: circ_0003418
Host Gene: -
 
 
 
Disease basic information
DO ID:
684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human HCC cell lines (Hep-3B, Huh-7, Sk-hep-1, SMMC-7721), normal human hepatocyte line (HL-77O2)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: Inhibits Tumorigenesis And Cisplatin Chemoresistance
Molecular mechanism: restraining the Wnt/beta-catenin pathway
Survival: -
Supported No.:
2
Description:

circ-0003418 exerts an antitumorigenic role in HCC and advances the sensitivity of HCC cells to cisplatin by restraining the Wnt/beta-catenin pathway.

Other information
Title:

circ_0003418 Inhibits Tumorigenesis And Cisplatin Chemoresistance Through Wnt/beta-Catenin Pathway In Hepatocellular Carcinoma.

Journal: Onco Targets Ther
Published: 2019/12/7
PubMed ID: 31807029