circRNA basic information
circBase ID: hsa_circ_0046600
Name: hsa_circ_B3GNTL1
Synonym: hsa-circ-0046600
Host Gene: hsa-miR-640
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HL-7702, SK-HEP-1, SMMC-7721, HepG2, HuH7, 293T
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HIF-1alpha
Associated microRNA: hsa-miR-640
Biological function: promotes Migration
Molecular mechanism: hsa-circ-0046600 is present mainly in the cytoplasm and promotes the expression of proteins such as HIF-1alpha by competitively binding to hsa-miR-640 in HCC
Survival: poor
Supported No.:
 2
Description:

hsa-circ-0046600 can be used as a new biomarker for HCC diagnosis and disease progression and provides a potential target for targeted therapy.
Other information
Title:

Emerging Roles Of hsa-circ-0046600 Targeting The miR-640/HIF-1alpha Signalling Pathway In The Progression Of HCC.

Journal: Onco Targets Ther
Published: 2019/12/7
PubMed ID: 31807009