circRNA basic information
circBase ID: hsa_circ_0051079
Name: hsa_circ_AKT2
Synonym: -
Host Gene: hsa-miR-26a-5p
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human osteosarcoma cell lines (HOS, KH-OS, MG63, 143B, U2OS, SaoS2), normal osteoblast cell line (hFOB1.19)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TGF-beta1
Associated microRNA: hsa-miR-26a-5p
Biological function: promotes the Proliferation and Migration
Molecular mechanism: regulating hsa-miR-26a-5p/TGF-beta1
Survival: -
Supported No.:
 3
Description:

The study demonstrated that circ_0051079 could act as an oncogene via regulating miR-26a-5p/TGF-beta1 and a potential biomarker for osteosarcoma diagnose.
Other information
Title:

Hsa_circ_0051079 functions as an oncogene by regulating miR-26a-5p/TGF-beta1 in osteosarcoma.

Journal: Cell Biosci
Published: 2019/12/5
PubMed ID: 31798828