circRNA basic information
circBase ID: hsa_circ_0085553
Name: hsa_circ_PVT1
Synonym: -
Host Gene: hsa-miR-124-3p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human GC tumor cell lines (MKN-45, HGC-27, MGC-803, AGS), normal human gastric epithelial cell line (GES-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ZEB1
Associated microRNA: hsa-miR-124-3p
Biological function: facilitated PTX resistance
Molecular mechanism: up-regulating ZEB1 mediated via hsa-miR-124-3p
Survival: -
Supported No.:
 6
Description:

circ-PVT1 facilitated PTX resistance by up-regulating ZEB1 mediated via miR-124-3p.
Other information
Title:

Circular RNA circ-PVT1 contributes to paclitaxel resistance of gastric cancer cells through the regulation of ZEB1 expression by sponging miR-124-3p.

Journal: Biosci Rep
Published: 2019/12/4
PubMed ID: 31793989