circRNA basic information
circBase ID: hsa_circ_0000515
Name: hsa_circ_RPPH1
Synonym: -
Host Gene: hsa-miR-326
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: cervical cancer cell lines (Hela, U14, SiHa, CaSki), normal cervical epithelial cells (H8)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ELK1
Associated microRNA: hsa-miR-326
Biological function: enhanced proliferation and invasion but repressed apoptosis and autophagy of cervical cancer cells
Molecular mechanism: increase ELK1
Survival: -
Supported No.:
 2
Description:

hsa_circ_0000515 acts as a tumor promoter in cervical cancer.
Other information
Title:

Circular RNA hsa_circ_0000515 acts as a miR-326 sponge to promote cervical cancer progression through up-regulation of ELK1.

Journal: Aging (Albany NY)
Published: 2019/11/28
PubMed ID: 31772143