circRNA basic information
circBase ID: -
Name: hsa_circ_LMTK2
Synonym: -
Host Gene: hsa-miR-183
 
 
 
Disease basic information
DO ID:
 10283
DO name: prostate cancer
Disease details: prostate cancer
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-183
Biological function: suppressed cell proliferation and metastasis, however promoted cell apoptosis
Molecular mechanism: the inhibitory effects on Wnt/beta-catenin and PI3K/AKT pathways evoked by circLMTK2 overexpression were diminished by hsa-miR-183 up-regulation
Survival: -
Supported No.:
 1
Description:

circLMTK2 overexpression exerts an anti-tumor effects through down-regulating the expression of miR-183.
Other information
Title:

CircLMTK2 acts as a tumor suppressor in prostate cancer via regulating the expression of microRNA-183.

Journal: Life Sci
Published: 2019/11/25
PubMed ID: 31760099