circRNA basic information
circBase ID: -
Name: hsa_circ_VANGL1
Synonym: -
Host Gene: hsa-miR-1184
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human bladder epithelium immortalized cell line (SV_HUC) , BC cell lines (T24, EJ, J82, RT_4, UM_UC_3, TCC)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: IGFBP2
Associated microRNA: hsa-miR-1184
Biological function: promote Cell invasion and migration
Molecular mechanism: upregulated the expression of hsa-miR-1184 target gene insulin-like growth factor-binding protein 2 (IGFBP2) by sponging hsa-miR-1184, which promoted the aggressive biological behaviors of BC
Survival: -
Supported No.:
 3
Description:

circVANGL1 acts as a tumor promoter through the novel circVANGL1/miR-1184/IGFBP2 axis.
Other information
Title:

Silencing circular RNA VANGL1 inhibits progression of bladder cancer by regulating miR-1184/IGFBP2 axis.

Journal: Cancer Med
Published: 2019/11/24
PubMed ID: 31758655