circRNA basic information
circBase ID: -
Name: hsa_circ_MTDH4
Synonym: -
Host Gene: hsa-miR-630
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human bronchial epithelial cell line cells (BEAS_2B), NSCLC cell lines (NCI_H1650, NCI_H358, HCC827, NCI_1299, A549)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: AEG-1
Associated microRNA: hsa-miR-630
Biological function: promote cell proliferation, migration, invasion, and chemoresistance/radioresistance
Molecular mechanism: upregulating AEG-1
Survival: -
Supported No.:
 1
Description:

circMTDH.4 regulated AEG-1 expression via sponging miR-630.
Other information
Title:

circMTDH4/miR-630/AEG-1 axis participates in the regulation of proliferation, migration, invasion, chemoresistance, and radioresistance of NSCLC.

Journal: Mol Carcinog
Published: 2019/11/22
PubMed ID: 31749230