circRNA basic information
circBase ID: -
Name: hsa_circ_ZFR
Synonym: -
Host Gene: hsa-miR-377
 
 
 
Disease basic information
DO ID:
11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ZEB2
Associated microRNA: hsa-miR-377
Biological function: increased cell proliferation, migration and invasion
Molecular mechanism: directly bind to hsa-miR-377 as sponge to promote ZEB2 expression
Survival: poor
Supported No.:
3
Description:

circZFR could be a prognostic biomarker in bladder cancer and exerted oncogenic roles through regulating miR-377/ZEB2 axis in bladder cancer.

Other information
Title:

CircZFR serves as a prognostic marker to promote bladder cancer progression by regulating miR-377/ZEB2 signaling.

Journal: Biosci Rep
Published: 2019/11/21
PubMed ID: 31746333