circRNA basic information
circBase ID: -
Name: hsa_circ_ESRP1
Synonym: cESRP1
Host Gene: hsa-miR-93-5p
 
 
 
Disease basic information
DO ID:
 5409
DO name: lung small cell carcinoma
Disease details: small cell lung cancer
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TGF-beta
Associated microRNA: hsa-miR-93-5p
Biological function: sensitises small cell lung cancer cells to chemotherapy
Molecular mechanism: sponging hsa-miR-93-5p to inhibit TGF-beta signalling.
Survival: -
Supported No.:
 1
Description:

The cESRP1 plays crucial a role in SCLC chemosensitivity by sponging miR-93-5p to inhibit the TGF-beta pathway.
Other information
Title:

Circular RNA cESRP1 sensitises small cell lung cancer cells to chemotherapy by sponging miR-93-5p to inhibit TGF-beta signalling.

Journal: Cell Death Differ
Published: 2019/11/16
PubMed ID: 31728016