circRNA basic information
circBase ID: -
Name: -
Synonym: circ_0102049
Host Gene: hsa-miR-1304-5p
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: OS cells (MG63, HOS, Saos2, U2OS), corresponding normal cells (hFOB1.19)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MDM2
Associated microRNA: hsa-miR-1304-5p
Biological function: increased cell proliferation, migration and invasion, and inhibited cell apoptosis
Molecular mechanism: sponge hsa-miR-1304-5p to upregulate MDM2
Survival: poor
Supported No.:
 2
Description:

Circ_0102049 remarkably accelerated cell proliferation, migration and invasion but attenuated cell apoptosis in OS cells.
Other information
Title:

Circular RNA circ_0102049 promotes cell progression as ceRNA to target MDM2 via sponging miR-1304-5p in osteosarcoma.

Journal: Pathol Res Pract
Published: 2019/11/16
PubMed ID: 31727503