circRNA basic information
circBase ID: -
Name: hsa_circ_LMTK2
Synonym: -
Host Gene: hsa-miR-150-5p
 
 
 
Disease basic information
DO ID:
10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: c-Myc
Associated microRNA: hsa-miR-150-5p
Biological function: promotes proliferation and metastasis
Molecular mechanism: sponge hsa-miR-150-5p, thus indirectly regulating the c-Myc expression
Survival: -
Supported No.:
2
Description:

circLMTK2 functions as a tumour promoter in GC through the miR-150-5p/c-Myc axis and could thus be a prognostic predictor and therapeutic target for GC.

Other information
Title:

circLMTK2 acts as a sponge of miR-150-5p and promotes proliferation and metastasis in gastric cancer.

Journal: Mol Cancer
Published: 2019/11/15
PubMed ID: 31722712