circRNA basic information
circBase ID: -
Name: hsa_circ_GRAMD1B
Synonym: -
Host Gene: hsa-miR-130a-3p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human GC cell lines (AGS, SGC7901, MKN28, MKN45, MGC803, BGC823)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PTEN, p21
Associated microRNA: hsa-miR-130a-3p
Biological function: inhibited cell proliferation, migration and invasion
Molecular mechanism: inhibited cell proliferation, migration and invasion
Survival: -
Supported No.:
 1
Description:

circGRAMD1B plays an important role in GC progression by regulating miR-130a-3p-PTEN/p21, which may provide a potential biomarker and therapeutic target for GC.
Other information
Title:

Circular RNA circGRAMD1B inhibits gastric cancer progression by sponging miR-130a-3p and regulating PTEN and p21 expression.

Journal: Aging (Albany NY)
Published: 2019/11/14
PubMed ID: 31719211