circRNA basic information
circBase ID: hsa_circ_0075341
Name: hsa_circ_MAPK9
Synonym: -
Host Gene: hsa-miR-149-5p
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: AURKA
Associated microRNA: hsa-miR-149-5p
Biological function: promote cell proliferation, invasion
Molecular mechanism: AURKA was confirmed as a direct target of hsa-miR-149-5p in cervical cancer and positively regulated by hsa_circ_0075341.
Survival: poor
Supported No.:
 1
Description:

hsa_circ_0075341 promoted cervical cancer cell proliferation and invasion through regulating the miR-149-5p/AURKA axis, which provided a novel therapeutic target for cervical cancer treatment.
Other information
Title:

Hsa_circ_0075341 is up-regulated and exerts oncogenic properties by sponging miR-149-5p in cervical cancer.

Journal: Biomed Pharmacother
Published: 2019/11/11
PubMed ID: 31706100