circRNA basic information
circBase ID: -
Name: -
Synonym: circ_016719
Host Gene: mmu-miR-29c
 
 
 
Disease basic information
DO ID:
 6713
DO name: cerebrovascular disease
Disease details: stroke
Species: mouse
Species details: mouse
Sample type: cell line
Sample type details: mouse hippocampal neuron cell line (HT22)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: Map2k6
Associated microRNA: mmu-miR-29c
Biological function: pro-apoptotic
Molecular mechanism: directly targets mmu-miR-29c, and thereby regulates the expression and functions of Map2k6
Survival: -
Supported No.:
 1
Description:

circ_016719 directly targets miR-29c, and thereby regulates the expression and functions of Map2k6, which significantly contributes to the pro-apoptotic role of circ_016719.
Other information
Title:

Circ_016719 plays a critical role in neuron cell apoptosis induced by I/R via targeting miR-29c/Map2k6.

Journal: Mol Cell Probes
Published: 2019/11/8
PubMed ID: 31698040