circRNA basic information
circBase ID: hsa_circ_0005273
Name: -
Synonym: circ_0005273
Host Gene: hsa-miR-1183
 
 
 
Disease basic information
DO ID:
 3969
DO name: thyroid gland papillary carcinoma
Disease details: papillary thyroid cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HEK-293T, human PTC cell lines (KTC-1, IHH-4, BCPAP, TPC-1), thyroid follicular epithelial cell line (Nthy-ori3-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SOX2
Associated microRNA: hsa-miR-1183
Biological function: functioned as a tumor promoter
Molecular mechanism: circ_0005273/hsa-miR-1183/SOX2 axis
Survival: -
Supported No.:
 1
Description:

circ_0005273 functioned as a tumor promoter of PTC via circ_0005273/miR-1183/SOX2 axis, suggesting a novel biomarker and therapeutic target for PTC.
Other information
Title:

circ_0005273 promotes thyroid carcinoma progression by SOX2 expression.

Journal: Endocr Relat Cancer
Published: 2019/11/7
PubMed ID: 31693489