circRNA basic information
circBase ID: hsa_circ_0001971
Name: -
Synonym: circRNA_0001971
Host Gene: hsa-miR-186-5p
 
 
 
Disease basic information
DO ID:
 50866
DO name: oral squamous cell carcinoma
Disease details: oral squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HSC_3, SCC_4, CAL_27
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-186-5p
Biological function: Silencing circRNA_0001971 attenuated the malignancy of OSCC cells by suppressing proliferation, migration, and invasion.
Molecular mechanism: In OSCC cells, circRNA_0001971 sponged hsa-miR-186-5p to enhance FNDC3B.
Survival: -
Supported No.:
 3
Description:

Overall, our study discovered that circRNA_0001971 was a tumor promoter in OSCC progression by targeting miR-186-5p/FNDC3B axis.
Other information
Title:

Hsa_circRNA_0001971 contributes to oral squamous cell carcinoma progression via miR-186-5p/Fibronectin type III domain containing 3B axis.

Journal: J Clin Lab Anal
Published: 2022/1/22
PubMed ID: 35060189