circRNA basic information
circBase ID: -
Name: hsa_circ_ZNF292
Synonym: cZNF292
Host Gene: hsa-miR-206
 
 
 
Disease basic information
DO ID:
 5041
DO name: esophageal cancer
Disease details: esophageal cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: Eca-109 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-206
Biological function: promote the growth, migration, and invasion
Molecular mechanism: cZNF292 silencing upregulated hsa-miR-206 expression. And hsa-miR-206 downregulation impaired the suppressive effects of cZNF292 silence toward Eca-109 cell growth, migration, and invasion. cZNF292 silencing activated AMPK signaling and inactivated PI3K/AKT signaling also via regulating hsa-miR-206
Survival: -
Supported No.:
 1
Description:

silencing of cZNF292 abated growth, migration, and invasion of Eca-109 cells by upregulating miR-206, which subsequently modulated AMPK and PI3K/AKT signaling pathways.
Other information
Title:

Silence of cZNF292 suppresses the growth, migration, and invasion of human esophageal cancer Eca-109 cells via upregulating miR-206.

Journal: J Cell Biochem
Published: 2019/11/5
PubMed ID: 31680303