circRNA basic information
circBase ID: -
Name: -
Synonym: circ_0080425
Host Gene: hsa-miR-24-3p
 
 
 
Disease basic information
DO ID:
 557
DO name: kidney disease
Disease details: diabetic nephropathy
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: Mouse mesangial cells (MCs)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FGF11
Associated microRNA: hsa-miR-24-3p
Biological function: inhibits cell proliferation and fibrosis
Molecular mechanism: sponging hsa-miR-24-3p and targeting fibroblast growth factor 11
Survival: -
Supported No.:
 1
Description:

circ_0080425 competitive binding to miR-24-3p could release FGF11 from miR-24-3p suppression, which subsequently promoted DN progression.
Other information
Title:

Circ_0080425 inhibits cell proliferation and fibrosis in diabetic nephropathy via sponging miR-24-3p and targeting fibroblast growth factor 11.

Journal: J Cell Physiol
Published: 2019/11/5
PubMed ID: 31680239