circRNA basic information
circBase ID: -
Name: hsa_circ_EZH2
Synonym: circ-EZH2
Host Gene: hsa-miR-1265
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: glioma cell lines (U87MG, U251, U118, LN229), normal human astrocytes (NHA)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: DDAH1 and CBX3
Associated microRNA: hsa-miR-1265
Biological function: promote cell growth and invasion
Molecular mechanism: circ-EZH2 served as a miRNA sponge for hsa-miR-1265 to release its suppression on DDAH1 and CBX3.
Survival: -
Supported No.:
 1
Description:

circ-EZH2 served as a miRNA sponge for miR-1265 to release its suppression on DDAH1 and CBX3.
Other information
Title:

Circ-EZH2 knockdown reverses DDAH1 and CBX3-mediated cell growth and invasion in glioma through miR-1265 sponge activity.

Journal: Gene
Published: 2019/11/2
PubMed ID: 31669648