circRNA basic information
circBase ID: -
Name: hsa_circ_USP1
Synonym: -
Host Gene: hsa-miR-194-5p
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: cell line
Sample type details: immortalized human cerebral microvascular endothelial cell line (hCMEC/D3, ECs), human glioma cell line (U87MG), human embryonic kidney 293T cell line (HEK293T)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FLI1
Associated microRNA: hsa-miR-194-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

the crucial regulation of circ-USP1 on BTB permeability via miR-194-5p/FLI1 axis-mediated regulation of tight junction proteins, which might facilitate the development of therapeutics against human gliomas.
Other information
Title:

Circular RNA USP1 regulates the permeability of blood-tumour barrier via miR-194-5p/FLI1 axis.

Journal: J Cell Mol Med
Published: 2019/10/28
PubMed ID: 31654502