circ_FAM53B could be a competing endogenous RNA (ceRNA) to competitively sponge miR_646 and miR_647 to upregulate VAMP2 and MDM2 expression at the post_transcriptional level, thus mediating the cellular behaviors of OC cells.
Upregulation of circular RNA circ_FAM53B predicts adverse prognosis and accelerates the progression of ovarian cancer via the miR_646/VAMP2 and miR_647/MDM2 signaling pathways.