circRNA basic information
circBase ID: -
Name: hsa_circ_PTN
Synonym: -
Host Gene: hsa-miR-122
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: cell line
Sample type details: normal human glial cell line (HEB), human glioma cell lines (U251, U87)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-122
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 3
Description:

Circ_PTN acted as a sponge of miR-122 and upregulated miR-122 target SOX6, thus promoting carcinogenesis of glioma cells.
Other information
Title:

Circular RNA Pleiotrophin promotes carcinogenesis in glioma via regulation of microRNA-122/SRY-box transcription factor 6 axis.

Journal: Eur J Cancer Prev
Published: 2019/10/15
PubMed ID: 31609809