circRNA basic information
circBase ID: hsa_circ_0000284
Name: hsa_circ_HIPK3
Synonym: -
Host Gene: hsa-miR-17-3p
 
 
 
Disease basic information
DO ID:
 114
DO name: heart disease
Disease details: heart failure
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: primary NMCMs (neonatal mouse cardiomyocytes)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ADCY6
Associated microRNA: hsa-miR-17-3p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 4
Description:

the increased circ-HIPK3 can be a helper for adrenaline but was harmful for heart in the long run and might be an ideal therapeutic target of HF.
Other information
Title:

Circ-HIPK3 Strengthens the Effects of Adrenaline in Heart Failure by MiR-17-3p - ADCY6 Axis.

Journal: Int J Biol Sci
Published: 2019/10/9
PubMed ID: 31595165