circRNA basic information
circBase ID: hsa_circ_0015756
Name: hsa_circ_CFH
Synonym: circ_0015756
Host Gene: hsa-miR-7
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human fetal hepatic cell line (WRL-68 cells), HCC cell lines (MHCC97H, Bel-7402, Huh-7, Bel100)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FAK
Associated microRNA: hsa-miR-7
Biological function: promotes proliferation, invasion and migration
Molecular mechanism: up-regulate FAK via targeting hsa-miR-7.
Survival: -
Supported No.:
 3
Description:

Circ_0015756 knockdown was shown to increase the expression of miR-7, reduce the proliferation, invasion, migration and resistance to apoptosis, and down-regulate the expression of FAK in HCC.
Other information
Title:

Circ_0015756 promotes proliferation, invasion and migration by microRNA-7-dependent inhibition of FAK in hepatocellular carcinoma.

Journal: Cell Cycle
Published: 2019/9/17
PubMed ID: 31522588