circRNA basic information
circBase ID: -
Name: hsa_circ_PTN
Synonym: circPTN
Host Gene: hsa-miR-145-5p, hsa-miR-330-5p
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: U251
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-145-5p, hsa-miR-330-5p
Biological function: promote proliferation and stemness
Molecular mechanism: rescued the inhibition of proliferation and downregulation of SOX9/ITGA5 in glioma cells by hsa-miR-145-5p/hsa-miR-330-5p
Survival: -
Supported No.:
 3
Description:

circPTN is an oncogenic factor that acts by sponging miR-145-5p/miR-330-5p in glioma.
Other information
Title:

circPTN sponges miR-145-5p/miR-330-5p to promote proliferation and stemness in glioma.

Journal: J Exp Clin Cancer Res
Published: 2019/9/13
PubMed ID: 31511040