circRNA basic information
circBase ID: hsa_circ_0000284
Name: hsa_circ_HIPK3
Synonym: circ-0000284
Host Gene: -
 
 
 
Disease basic information
DO ID:
 4947
DO name: cholangiocarcinoma
Disease details: cholangiocarcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human cholangiocarcinoma cell lines (TFK-1, SNU-869, SSP-25, RBE, HuCCT1, HuH28), human normal bile duct cell line (H69)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: enhanced the migration, invasion and proliferation abilities
Molecular mechanism: -
Survival: -
Supported No.:
 2
Description:

on the one hand circ-0000284 functions as a competitive endogenous RNA to promote cholangiocarcinoma progression, and on the other hand, circ-0000284 can be directly transferred from cholangiocarcinoma cells to surrounding normal cells via exosomes.
Other information
Title:

Circ-0000284 arouses malignant phenotype of cholangiocarcinoma cells and regulates the biological functions of peripheral cells through cellular communication.

Journal: Clin Sci (Lond)
Published: 2019/9/11
PubMed ID: 31501232