circRNA basic information
circBase ID: -
Name: hsa_circ_LMNB1
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal colorectal cell line (FHC), human CRC cell lines (HT29, LoVo, HCT116, SW480, RKO)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: promote cell proliferation, migration and invasion, and inhibit cell cycle arrest and apoptosis
Molecular mechanism: -
Survival: -
Supported No.:
 2
Description:

Our findings revealed that blocking of circLMNB1 could inhibit CRC development, and help to explain the underlying mechanism by which circLMNB1 knockdown inhibits the metastasis of CRC.
Other information
Title:

CircLMNB1 promotes colorectal cancer by regulating cell proliferation, apoptosis and epithelial-mesenchymal transition.

Journal: Onco Targets Ther
Published: 2019/9/10
PubMed ID: 31496737