circRNA basic information
circBase ID: -
Name: hsa_circ_DENND4C
Synonym: -
Host Gene: hsa-miR-200b, hsa-miR-200c
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: breast cancer cell lines (MDA-MB-453, SK-BR-3), normal human breast epithelial cells (MCF-10A)
circRNA-disease information
Detected method:
S
Detected method confidence Low
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-200b, hsa-miR-200c
Biological function: promote glycolysis, migration and invasion
Molecular mechanism: decreasing hsa-miR-200b and hsa-miR-200c
Survival: -
Supported No.:
 2
Description:

circDENND4C silence suppresses glycolysis, migration and invasion in breast cancer cells under hypoxia by increasing miR-200b and miR-200c.
Other information
Title:

Knockdown of circDENND4C inhibits glycolysis, migration and invasion by up-regulating miR-200b/c in breast cancer under hypoxia.

Journal: J Exp Clin Cancer Res
Published: 2019/9/7
PubMed ID: 31488193