circRNA basic information
circBase ID: hsa_circ_0001022
Name: hsa_circ_ACTR2
Synonym: circular RNA_000926
Host Gene: hsa-miR-411
 
 
 
Disease basic information
DO ID:
 4451
DO name: renal carcinoma
Disease details: renal carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: RCC cell lines (786-O, A498, 769-P, ACHN), normal kidney cell line HK-2 (ZY-H507)
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: CDH2
Associated microRNA: hsa-miR-411
Biological function: promote growth, migration, invasion, epithelial-mesenchymal transition and tumor growth
Molecular mechanism: directly bind to hsa-miR-411 to up-regulate CDH2.
Survival: -
Supported No.:
 1
Description:

Down-regulation of circ_000926 exerts an inhibitory effect on RCC progression through miR-411-dependent CDH2 inhibition.
Other information
Title:

Down-Regulation of Circular RNA_000926 Attenuates Renal Cell Carcinoma Progression through miRNA-411-Dependent CDH2 Inhibition.

Journal: Am J Pathol
Published: 2019/9/3
PubMed ID: 31476285