circRNA basic information
circBase ID: hsa_circ_0000594
Name: hsa_circ_TTBK2
Synonym: -
Host Gene: hsa-miR-217
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human glioma cell lines (U87, U251), human embryonic kidney cells (293T)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-217
Biological function: promotes cell proliferation, migration, and invasion
Molecular mechanism: regulating hsa-miR-217/HNF1beta/Derlin-1 pathway
Survival: poor
Supported No.:
 4
Description:

Enhanced expression of circ-TTBK2 promoted cell proliferation, migration, and invasion, while inhibited apoptosis.
Other information
Title:

TTBK2 circular RNA promotes glioma malignancy by regulating miR-217/HNF1beta/Derlin-1 pathway.

Journal: J Hematol Oncol
Published: 2017/2/22
PubMed ID: 28219405