circRNA basic information
circBase ID: -
Name: hsa_circ_CBL11
Synonym: circRNA CBL.11
Host Gene: hsa-miR-6778-5p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human colon epithelial cell line (NCM460), human colon cancer cell lines (HCT116, SW620), human colon adenocarcinoma cell line (HT29), human embryonic kidney cell line (HEK293T)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-6778-5p
Biological function: suppresses cell proliferation
Molecular mechanism: suppresses p53 pathway
Survival: -
Supported No.:
 1
Description:

After carbon ion irradiation, circRNA CBL.11 was increased in CRC cells and could function as a competing endogenous RNA (ceRNA) to regulate YWHAE expression by sponging miR-6778-5p, resulting in regulation the proliferation of CRC cells.
Other information
Title:

CircRNA CBL11 suppresses cell proliferation by sponging miR-6778-5p in colorectal cancer.

Journal: BMC Cancer
Published: 2019/8/24
PubMed ID: 31438886