circRNA basic information
circBase ID: -
Name: hsa_circ_MYLK
Synonym: -
Host Gene: hsa-miR-195
 
 
 
Disease basic information
DO ID:
 2876
DO name: laryngeal squamous cell carcinoma
Disease details: laryngeal squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: SCC15, CAL27
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: cyclin D1
Associated microRNA: hsa-miR-195
Biological function: promoted LSCC cell proliferation and G(1)/S cell cycle transition
Molecular mechanism: serve as a competing endogenous RNA for hsa-miR-195 to increase cyclin D1 expression in LSCC
Survival: -
Supported No.:
 1
Description:

circMYLK/miR-195/cyclin D1 regulatory axis could affect the proliferation and cell cycle progression of LSCC cells.
Other information
Title:

Circular RNA MYLK serves as an oncogene to promote cancer progression via microRNA-195/cyclin D1 axis in laryngeal squamous cell carcinoma.

Journal: Biosci Rep
Published: 2019/8/21
PubMed ID: 31427478